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Article

Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef.

Journal of virology - 1 Feb 2005

Keppler Oliver T, Allespach Ina, Schüller Lismarie, Fenard David, Greene Warner C, Fackler Oliver T

Abstract excerpt

After infection with human immunodeficiency virus (HIV), progression toward immunodeficiency is governed by a complex interplay of viral and host determinants. The viral accessory protein Nef is a key factor for the development of AIDS. Strains of HIV and simian immunodeficiency virus that lack functional nef genes either do not induce AIDS or do so only after a significant delay. The validity of a...

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Identifiers

PMID: 15650191
DOI: 10.1128/JVI.79.3.1655-1665.2005
PMCID: PMC544094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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