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Article

The CD4C/HIV(Nef)transgenic model of AIDS.

Current HIV research - 1 Oct 2011

Jolicoeur Paul

Abstract excerpt

CD4C/HIVNef Tg mice express HIV-1 Nef in relevant target cells through the regulatory sequences of the human CD4 gene. These mice develop a severe disease showing many characteristics of human AIDS. A summary of the results obtained with these Tg mice is presented.

Read the complete abstract on PubMed

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Share to Phenotype
Share to Acquired Immunodeficiency Syndrome
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Mice, Transgenic

Share to nef Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 22103836
DOI: 10.2174/157016211798842062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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