Article
The expression of intact and mutant human apoAI/CIII/AIV/AV gene cluster in transgenic mice.
The Journal of biological chemistry - 1 Apr 2005
Gao Jun, Wei Yusheng, Huang Yue, Liu Depei, Liu Guang, Wu Min, Wu Lin, Zhang Qingjun, Zhang Zhuqin, Zhang Ran, Liang Chihchuan
Abstract excerpt
The apoAI/CIII/AIV gene cluster is involved in lipid metabolism and has a complex pattern of gene expression modulated by a common regulatory element, the apoCIII enhancer. A new member of this cluster, apolipoprotein (apo) AV, has recently been discovered as a novel modifier in triglyceride metabolism. To determine the expression of all four apo genes in combination and, most importantly, whether the...
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