Article
The role and mode of action of apolipoproteins CIII and AV: synergistic actors in triglyceride metabolism?
Current opinion in lipidology - 1 Jun 2004
van Dijk Ko Willems, Rensen Patrick C N, Voshol Peter J, Havekes Louis M
Abstract excerpt
PURPOSE OF REVIEW: Apolipoprotein (apo)CIII and apoAV play an important role in triglyceride metabolism as evidenced by the unambiguous and opposing phenotypes of transgenic and knockout mouse models. In this review we discuss studies on the genetics, protein structure, and regulation of apoCIII and apoAV and compare their potential molecular mechanisms of action in triglyceride metabolism. We examine the...
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