Article
Neural progenitor cells from an adult patient with fragile X syndrome.
BMC medical genetics - 14 Jan 2005
Schwartz Philip H, Tassone Flora, Greco Claudia M, Nethercott Hubert E, Ziaeian Boback, Hagerman Randi J, Hagerman Paul J
Abstract excerpt
BACKGROUND: Currently, there is no adequate animal model to study the detailed molecular biochemistry of fragile X syndrome, the leading heritable form of mental impairment. In this study, we sought to establish the use of immature neural cells derived from adult tissues as a novel model of fragile X syndrome that could be used to more fully understand the pathology of this neurogenetic disease. METHODS: By...
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