Article
CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases.
Pigment cell research - 1 Feb 2005
Blomhoff Anne, Kemp E Helen, Gawkrodger David J, Weetman Anthony P, Husebye Eystein S, Akselsen Hanne E, Lie Benedicte A, Undlien Dag E
Abstract excerpt
The cytotoxic T lymphocyte antigen4 (CTLA4) gene plays a critical role in the control of T cell activation. The gene encodes a surface molecule with inhibitory effects on activated T cells. Several studies have disclosed an association between the previously known variants of the CTLA4 gene and autoimmune disorders, but no study has as yet found any definite association between vitiligo and the CTLA4...
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