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Article

Self-assembled TNT biosensor based on modular multifunctional surface-tethered components.

Analytical chemistry - 15 Jan 2005

Medintz Igor L, Goldman Ellen R, Lassman Michael E, Hayhurst Andrew, Kusterbeck Anne W, Deschamps Jeffrey R

Abstract excerpt

We demonstrate a self-assembled reagentless biosensor based on a modular design strategy that functions in the detection of TNT and related explosive compounds. The sensor consists of a dye-labeled anti-TNT antibody fragment that interacts with a cofunctional surface-tethered DNA arm. The arm consists of a flexible biotinylated DNA oligonucleotide base specifically modified with a dye and terminating in a TNB...

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PMID: 15649029
DOI: 10.1021/ac048485n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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