Article
Novel signal amplification technology with applications in DNA and protein detection systems.
BioTechniques - 1 Jun 2001
Lisle C M, Bortolin S, Benight A S, Janeczko R A, Zastawny R L
Abstract excerpt
A non-enzymatic approach to signal amplification has practical advantages over conventional target amplification methods. We have designed a simple, cost-efficient signal amplification system that can be used to enhance the detection of nucleic acids or protein. The signal amplification process requires initial capture of analyte by a specific probe, which, depending on the analyte, can be an oligomer or an...
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