Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Organelle-specific control of intracellular transport: distinctly targeted isoforms of the regulator Klar.

Molecular biology of the cell - 1 Mar 2005

Guo Yi, Jangi Sushrut, Welte Michael A

Abstract excerpt

Microtubule-based transport in cells is powered by a small set of distinct motors, yet timing and destination of transport can be controlled in a cargo-specific manner. The mechanistic basis for this specificity is not understood. To address this question, we analyzed the Drosophila Klarsicht (Klar) protein that regulates distinct microtubule-based transport processes. We find that localization of Klar to its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunoblotting
Share to In Situ Hybridization
Share to Lipid Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Luminescent Proteins

Share to Microtubules

Share to Nuclear Envelope

Share to Red Fluorescent Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 15647372
DOI: 10.1091/mbc.e04-10-0920
PMCID: PMC551502

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Organelle-specific control of intracellular transport: distinctly targeted isoforms of the regulator Klar.PMID 15647372Read ↗

Novel isoforms of the transport regulator klar.Semantic proximity Read ↗

Targeting the motor regulator Klar to lipid droplets.Semantic proximity Read ↗

Molecular analysis of the klarsicht gene and its role in nuclear migration within differentiating cells of the Drosophila eye.Semantic proximity Read ↗

Drosophila klarsicht has distinct subcellular localization domains for nuclear envelope and microtubule localization in the eye.Semantic proximity Read ↗

Drosophila klaroid encodes a SUN domain protein required for Klarsicht localization to the nuclear envelope and nuclear migration in the eye.Semantic proximity Read ↗

Organelle positioning in muscles requires cooperation between two KASH proteins and microtubules.Semantic proximity Read ↗

PIP5K-dependent production of PIP2 sustains microtubule organization to establish polarized transport in the Drosophila oocyte.Semantic proximity Read ↗

Domains of the Pavarotti kinesin-like protein that direct its subcellular distribution: effects of mislocalisation on the tubulin and actin cytoskeleton during Drosophila oogenesis.Semantic proximity Read ↗

On the roles of the Drosophila KASH domain proteins Msp-300 and Klarsicht.Semantic proximity Read ↗

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly.Semantic proximity Read ↗

The receptor-like tyrosine phosphatase lar is required for epithelial planar polarity and for axis determination within drosophila ovarian follicles.Semantic proximity Read ↗

A spectraplakin is enriched on the fusome and organizes microtubules during oocyte specification in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.