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Article

Pretransplant NPM1 MRD levels predict outcome after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia.

Blood cancer journal - 29 Jul 2016

Kayser S, Benner A, Thiede C, Martens U, Huber J, Stadtherr P, Janssen J W G, Röllig C, Uppenkamp M J, Bochtler T, Hegenbart U, Ehninger G, Ho A D, Dreger P, Krämer A

Abstract excerpt

The objective was to evaluate the prognostic impact of pre-transplant minimal residual disease (MRD) as determined by real-time quantitative polymerase chain reaction in 67 adult NPM1-mutated acute myeloid leukemia patients receiving allogeneic hematopoietic stem cell transplantation (HSCT). Twenty-eight of the 67 patients had a FLT3-ITD (42%). Median age at transplantation was 54.7 years, median follow-up for...

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Identifiers

PMID: 27471865
DOI: 10.1038/bcj.2016.46
PMCID: PMC5030374

Genes

NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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