Article
Correlation of minimal residual disease cell frequency with molecular genotype in patients with acute myeloid leukemia.
Haematologica - 1 Jan 2009
Hess Corine J, Feller Nicole, Denkers Fedor, Kelder Angèle, Merle Pauline A, Heinrich Michael C, Harlow Amy, Berkhof Johannes, Ossenkoppele Gert J, Waisfisz Quinten, Schuurhuis Gerrit J
Abstract excerpt
BACKGROUND: About 70-80 percent of patients with acute myeloid leukemia enter complete remission, but at least half of these patients who achieve remission go on to relapse. Improved treatment is likely to come from increasing the time to relapse, especially for younger patients. With the vastly increasing number of targeted therapies there is a strong need for short-term end-points to efficiently test such...
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