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Article

IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4.

Experimental gerontology - 1 Aug 2006

Grallert Harald, Huth Cornelia, Kolz Melanie, Meisinger Christa, Herder Christian, Strassburger Klaus, Giani Guido, Wichmann H-Erich, Adamski Jerzy, Illig Thomas, Rathmann Wolfgang

Abstract excerpt

Interleukin-6 (IL-6) is a pleiotropic cytokine which has been proposed as "cytokine for gerontologists" and linked to age-related metabolic disturbances such as the metabolic syndrome or type 2 diabetes. Polymorphisms located in the promoter region of IL-6 have been reported to be involved in the regulation of IL-6 transcription. This study investigates whether IL-6 promoter variants -174 G/C and -573 G/C are...

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Identifiers

PMID: 16797905
DOI: 10.1016/j.exger.2006.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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