Article
Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3.
Genetics - 1 Jul 1997
McKee A H, Kleckner N
Abstract excerpt
Two new meiosis-specific genes, SAE1 and SAE3, have been identified in a screen for mutations that confer an intermediate block in meiotic prophase. Such mutations confer a block to spore formation that is circumvented by addition of a mutation that eliminates meiotic recombination initiation and...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosomes, Fungal
- Cloning, Molecular
- DNA Primers
- DNA, Fungal
- Fungal Proteins
- Genes, cdc
- Humans
- Meiosis
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Nuclear Cap-Binding Protein Complex
- Phenotype
- Phosphoproteins
- Prophase
- Recombinases