Article
Unveiling the etiological impact of GST-M1, GST-T1, and P53 genotypic variations on brain carcinogenesis.
Molecular biology reports - 29 Dec 2023
Dirican Onur, Kaygın Pınar, Oğuztüzün Serpil, Husseini Abbas Ali, Sarıaltın Sezen Yılmaz, Yılmaz Can, Ünlü Nihan, İzci Yusuf
Abstract excerpt
BACKGROUND: Functional variants of glutathione-S-transferase (GST)-M1, GST-T1, p53 might modulate brain cancer risk by altering the rate of metabolism and clearance of carcinogens from the brain tissue. In this study, the role of GST-M1, GST-T1, p53 polymorphisms on brain tumor was investigated. METHODS AND RESULTS: Brain tumor tissues of 143 patients were obtained from the Gulhane Training and Research Hospital,...
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