Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of a single nucleotide polymorphism in the IL-6 promoter region of ancient nuclear DNA.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2005

Larcombe Linda A, Nickerson Peter, Hoppa Robert D, Matheson Carney

Abstract excerpt

In the current study a method was developed to examine the G/C single nucleotide polymorphism (SNP) at position -174 in the IL-6 promoter from nuclear DNA samples isolated from human skeletal remains from Manitoba, Canada, dating to as early as 3500 years ago. The IL-6 (-174) SNP was detected in three ancient samples and determined, as expected, in three out of three to be homozygous G/G. The analysis of cytokine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to History, Ancient

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Indians, North American

Share to Interleukin-6

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 15639743
DOI: 10.1016/j.meegid.2004.07.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of a single nucleotide polymorphism in the IL-6 promoter region of ancient nuclear DNA.PMID 15639743Read ↗

An accurate, high-throughput method for genotyping the -373AnTn polymorphism in the interleukin-6 promoter.Semantic proximity Read ↗

Interleukin-6 promoter polymorphism at position -174 in giant cell arteritis.Semantic proximity Read ↗

Molecular screening of interleukin-6 gene promoter and influence of -174G/C polymorphism on breast cancer.Semantic proximity Read ↗

IL-6 polymorphisms: a useful genetic tool for inflammation research?Semantic proximity Read ↗

Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women.Semantic proximity Read ↗

Modest implication of interleukin-6 promoter polymorphisms in longevity.Semantic proximity Read ↗

A novel NlaIII polymorphism in the human IL-6 promoterSemantic proximity Read ↗

Effects of 174 G/C polymorphism in the promoter region of the interleukin-6 gene on plasma IL-6 levels and muscle strength in elderly women.Semantic proximity Read ↗

A novel single nucleotide polymorphism and five probable haplotypes in the 5' flanking region of the IL-6 gene in African-Americans.Semantic proximity Read ↗

Identification and efficient genotyping of an (A)n/(T)m polymorphism within the 5' untranslated region of the human IL6 gene.Semantic proximity Read ↗

A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density.Semantic proximity Read ↗

Analysis of an interleukin-6 gene promoter polymorphism in women with endometriosis by pyrosequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.