Expression of mutant p53 gene in squamous carcinoma arising in patients with recessive dystrophic epidermolysis bullosa.

doi:10.1111/j.1365-2559.1992.tb00962.x

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Article

Expression of mutant p53 gene in squamous carcinoma arising in patients with recessive dystrophic epidermolysis bullosa.

Histopathology - 1 Mar 1992

Slater S D, McGrath J A, Hobbs C, Eady R A, McKee P H

Abstract excerpt

Epidermolysis bullosa, a rare genodermatosis, is characterized by increased skin fragility manifest as blistering and sometimes accompanied by scarring. The latter is particularly severe in the recessive dystrophic variant and may be complicated by the development of squamous carcinoma in up to 3...

Topics

Carcinoma, Squamous Cell
Epidermolysis Bullosa Dystrophica
Gene Expression
Genes, p53
Humans
Immunohistochemistry
Mutation
Skin Neoplasms

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