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Article

Differential regulation of phosphoglucose isomerase/autocrine motility factor activities by protein kinase CK2 phosphorylation.

The Journal of biological chemistry - 18 Mar 2005

Yanagawa Takashi, Funasaka Tatsuyoshi, Tsutsumi Soichi, Raz Tirza, Tanaka Nobutada, Raz Avraham

Abstract excerpt

Phosphoglucose isomerase (PGI; EC 5.3.1.9) is a cytosolic housekeeping enzyme of the sugar metabolism pathways that plays a key role in both glycolysis and gluconeogenesis. PGI is a multifunctional dimeric protein that extracellularly acts as a cytokine with properties that include autocrine motility factor (AMF)-eliciting mitogenic, motogenic, and differentiation functions, and PGI has been implicated in tumor...

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PMID: 15637053
DOI: 10.1074/jbc.M409457200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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