Article
Cancer, type 2 diabetes, and ageing: news from flies and worms.
Swiss medical weekly - 18 Dec 2004
Hafen E
Abstract excerpt
The tumour suppressor gene PTEN is, next to p53, the second most frequently mutated gene in human cancers. The genes TSC1 and TSC2 are mutated in the severe human syndrome called Tuberous Sclerosis. Patients with this disease have large benign tumours composed of large cells in the brain. The genetic dissection of pathways controlling the growth of cells, organs, and the entire organism in Drosophila has...
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