Article
Multiple meningiomas: differential involvement of the NF2 gene in children and adults.
Journal of medical genetics - 1 Jan 2005
Evans D G R, Watson C, King A, Wallace A J, Baser M E
Abstract excerpt
OBJECTIVE: To screen for NF2 mutations in people with meningiomas. METHODS: Lymphocyte or tumour DNA was analysed from 46 individuals from 36 families who presented with a meningioma at age < or =15 years without vestibular schwannoma (VS), or who had multiple meningiomas in adulthood before the diagnosis of VS. RESULTS: Eight of 13 people with meningioma and other features of neurofibromatosis 2 (NF2) had an...
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