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Article

Dynamin is involved in endolysosomal cholesterol delivery to the endoplasmic reticulum: role in cholesterol homeostasis.

Traffic (Copenhagen, Denmark) - 1 Jul 2006

Robinet Peggy, Fradagrada Alexandre, Monier Marie-Noëlle, Marchetti Marta, Cogny Anne, Moatti Nicole, Paul Jean-Louis, Vedie Benoit, Lamaze Christophe

Abstract excerpt

Cholesterol is one of the most essential membrane components in mammalian cells and plays a critical role in several cellular functions. It is now established that intracellular cholesterol transport contributes to the regulation of cellular cholesterol homeostasis by mechanisms that are yet poorly defined. In this study, we examined the role of clathrin- and dynamin-dependent trafficking on the regulatory...

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PMID: 16787396
DOI: 10.1111/j.1600-0854.2006.00435.x

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