Article
Families at high and low risk for depression: a 3-generation study.
Archives of general psychiatry - 1 Jan 2005
Weissman Myrna M, Wickramaratne Priya, Nomura Yoko, Warner Virginia, Verdeli Helen, Pilowsky Daniel J, Grillon Christian, Bruder Gerard
Abstract excerpt
BACKGROUND: The familial nature of early-onset major depressive disorder (MDD) has been documented in numerous family studies of adults and is supported by studies of offspring of parents with MDD, for whom the risk is more than 3-fold. None of the published high-risk studies have gone beyond 2 generations, and few have a longitudinal design. We report results of an approximately 20-year follow-up of families at...
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