Article
Transcriptional profiling of neuronal differentiation by human embryonal carcinoma stem cells in vitro.
Stem cells (Dayton, Ohio) - 1 Jan 2003
Przyborski Stefan Alexander, Smith Stanley, Wood Andrew
Abstract excerpt
Pluripotent stem cell lines can be induced to differentiate into a range of somatic cell types in response to various stimuli. Such cell-based systems provide powerful tools for the investigation of molecules that modulate cellular development. For instance, the formation of the nervous system is a highly regulated process, controlled by molecular pathways that determine the expression of specific proteins...
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