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Article

Autoregulatory role of interleukin-10 in hepatitis C patients treated with IFN-alpha.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Oct 2004

Luik Armin, Knapp Susanne, Thursz Mark, Thomas Howard C, Schlaak Jörg F

Abstract excerpt

Interferon-alpha2 (IFN-alpha2) is used as standard treatment of patients with chronic hepatitis C (cHCV), but little is known about the immunomodulatory effects of this cytokine in vivo. We have studied immunologic parameters in freshly isolated peripheral blood mononuclear cells (PBMC) of 26 patients with cHCV 12 h before and 12 h after the first s.c. injection of 5-6 MU IFN-alpha2. In PBMC obtained after IFN...

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Identifiers

PMID: 15626155
DOI: 10.1089/jir.2004.24.585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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