Article
Combined analysis of interferon-gamma and interleukin-10 gene polymorphisms and chronic hepatitis C severity.
Human immunology - 1 Apr 2009
Bouzgarrou Nadia, Hassen Elham, Farhat Karim, Bahri Olfa, Gabbouj Sallouha, Maamouri Nadia, Ben Mami Nabil, Saffar Hammouda, Trabelsi Abdelhalim, Triki Henda, Chouchane Lotfi
Abstract excerpt
Today there is increasing evidence concerning the contribution of pro-/anti-inflammatory cytokine balance and genetic factors in hepatitis C pathogenesis and interindividual heterogeneity of disease outcome. In the current study, we investigated the influence of functionally described single nucleotide polymorphisms (SNPs) present in interferon-gamma (IFNgamma) and interleukin-10 (IL-10) genes, on chronic...
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