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Article

Role of the streptokinase alpha-domain in the interactions of streptokinase with plasminogen and plasmin.

The Journal of biological chemistry - 4 Mar 2005

Bean Ronald R, Verhamme Ingrid M, Bock Paul E

Abstract excerpt

The role of the streptokinase (SK) alpha-domain in plasminogen (Pg) and plasmin (Pm) interactions was investigated in quantitative binding studies employing active site fluorescein-labeled [Glu]Pg, [Lys]Pg, and [Lys]Pm, and the SK truncation mutants, SK-(55-414), SK-(70-414), and SK-(152-414). Lysine binding site (LBS)-dependent and -independent binding were resolved from the effects of the lysine analog,...

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Source

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Identifiers

PMID: 15623524
DOI: 10.1074/jbc.M411637200
PMCID: PMC2292463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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