Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia

Abstract excerpt

For the oncogenesis of many malignancies, it is crucial to prevent the shortening of the telomeres by the action of telomerase. In this study, clinical data and disease outcomes were analyzed in conjunction with the telomerase activity (TA) and telomere length (TL) of peripheral blood mononuclear cells. The study was carried out in 22 patients with adult T-cell leukemia (ATL) (7 chronic and 15 acute types) and in...

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• Share to Cytomegalovirus and herpesvirus research
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