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Article

Similar humoral immunity parameters in chronic lymphocytic leukemia patients independent of VH gene mutation status.

Leukemia & lymphoma - 1 Dec 2004

Sinisalo Marjatta, Aittoniemi Janne, Koski Tomi, Tobin Gerard, Thunberg Ulf, Sundström Christer, Rosenquist Richard, Käyhty Helena, Vilpo Juhani

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is a clonal B-cell disorder, which has recently been divided into 2 subtypes based on the somatic hypermutation status of the immunoglobulin heavy chain (IgVH) genes. In patients with unmutated tumor cells the survival time is approximately half of that in mutated cases, but the reason for this difference is poorly understood. Since infections are the major cause of mortality in...

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PMID: 15621758
DOI: 10.1080/10428190400007763

Genes

ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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