Article

High calorie diet background alters the expression of sirtuins in the testes of mice under caloric restriction

2021-01-01

Abstract excerpt

Caloric restriction (CR) is considered one of the most efficient interventions that extend lifespan and healthspan by delaying the onset of many age-related diseases in a variety of organisms. CR appears to activate sirtuins, which in turn modulate a wide range of cellular activities related to pathophysiological conditions such as stress and inflammation, DNA repair, apoptosis, and the processes of aging. In this...

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Identifiers and source

Literature Corpus work: 35cb460e-f237-5602-9738-697d3d58a380
DOI: 10.1016/j.tma.2021.02.001

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