Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Collagen Triple Helix Repeat Containing 1, a Novel Secreted Protein in Injured and Diseased Arteries, Inhibits Collagen Expression and Promotes Cell Migration

24 Dec 2004

Abstract excerpt

Collagen triple helix repeat containing 1 (Cthrc1) was identified in a screen for differentially expressed sequences in balloon-injured versus normal arteries. Cthrc1 expression was not detectable in normal arteries. However, on injury it was transiently expressed by fibroblasts of the remodeling adventitia and by smooth muscle cells of the neointima. It was also found in the matrix of calcifying human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic aneurysm repair treatments
Share to Cell Adhesion Molecules Research
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15618538
DOI: 10.1161/01.res.0000154262.07264.12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Collagen Triple Helix Repeat Containing 1, a Novel Secreted Protein in Injured and Diseased Arteries, Inhibits Collagen Expression and Promotes Cell MigrationPMID 15618538Read ↗

Cthrc1 is a novel inhibitor of transforming growth factor-beta signaling and neointimal lesion formation.Semantic proximity Read ↗

The Role of Collagen Triple Helix Repeat Containing 1 in Injured Arteries, Collagen Expression, and Transforming Growth Factor β SignalingSemantic proximity Read ↗

CTHRC1, a novel gene with multiple functions in physiology, disease and solid tumors (Review)Semantic proximity Read ↗

Early growth response-1, a dynamic conduit in cardiovascular diseaseSemantic proximity Read ↗

Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteinsSemantic proximity Read ↗

Collagen inhibitory peptide R1R2 mediates vascular remodeling by decreasing inflammation and smooth muscle cell activation.Semantic proximity Read ↗

Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro.Semantic proximity Read ↗

COL8A1 regulates endothelial phenotype in inflammatory endothelial-to-mesenchymal transition.Semantic proximity Read ↗

The role of tenascin C in cardiovascular disease.Semantic proximity Read ↗

Identification of a Novel Family of Cell-surface Proteins Expressed in Human Vascular EndotheliumSemantic proximity Read ↗

Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblastsSemantic proximity Read ↗

A major role for RCAN1 in atherosclerosis progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.