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Article

The role of tenascin C in cardiovascular disease.

Cardiovascular research - 1 Oct 2011

Golledge Jonathan, Clancy Paula, Maguire Jane, Lincz Lisa, Koblar Simon

Abstract excerpt

The extracellular matrix protein tenascin C (TnC) is expressed in a variety of embryonic tissues, but its expression in adult arteries is co-incident with sites of vascular disease. TnC expression has been linked to the development and complications of intimal hyperplasia, pulmonary artery hypertension, atherosclerosis, myocardial infarction, and heart failure. This review identifies the growing collection of...

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PMID: 21712412
DOI: 10.1093/cvr/cvr183

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