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Article

CYP1A1 genotype-selective inhibition of benzo[a]pyrene activation by quercetin.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2005

Schwarz Dieter, Kisselev Pyotr, Roots Ivar

Abstract excerpt

Epidemiological studies suggest that food rich in quercetin and naringin may protect against certain types of lung cancer, and that genotype dependent inhibition of cytochrome P450 1A1 (CYP1A1)-mediated bioactivation of procarcinogens could be the underlying mechanism. We studied the inhibitory effects of quercetin and naringin on the terminal bioactivation step of benzo[a]pyrene (B[a]P), a member of the major...

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Identifiers

PMID: 15618000
DOI: 10.1016/j.ejca.2004.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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