Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulation of NF-kappaB activity associated with alteration in proliferative response in the spleen after burn injury.

Shock (Augusta, Ga.) - 1 Jan 2005

Phan Ho H, Cho Kiho, Nelson Heather A, Shin Soowan, Jeong Jayoung, Greenhalgh David G

Abstract excerpt

Alterations in proliferation status and cellular composition of immune organs are among key events in the modulation of immune function after burn injury. Nuclear factor (NF)-kappaB is a transcription factor that plays a pivotal role in the response to injury as well as immune cell differentiation and proliferation. In this study, we investigated the effects of burn injury on the activity of NF-kappaB and its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Burns
Share to Cytoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Densitometry

Share to Enzyme-Linked Immunosorbent Assay

Share to NF-kappa B

Share to Proliferating Cell Nuclear Antigen

Share to Spleen

Source

Identifiers

PMID: 15614135
DOI: 10.1097/01.shk.0000148052.66645.67

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulation of NF-kappaB activity associated with alteration in proliferative response in the spleen after burn injury.PMID 15614135Read ↗

The role of NF‐κB in lymphoid malignanciesSemantic proximity Read ↗

Differential expression and tissue compartmentalization of the inflammatory response following thermal injury.Semantic proximity Read ↗

Signal transduction via the NF‐κB pathway: a targeted treatment modality for infection, inflammation and repairSemantic proximity Read ↗

Role of NF-kappaB in the control of apoptotic and proliferative responses in IL-2-responsive T cellsSemantic proximity Read ↗

T cells from burn-injured mice demonstrate a loss of sensitivity to glucocorticoids.Semantic proximity Read ↗

Burn injury-mediated alterations in cell cycle progression in lymphoid organs of mice.Semantic proximity Read ↗

CD4- CD8- TCR alpha/beta+ suppressor T cells demonstrated in mice 1 day after thermal injury.Semantic proximity Read ↗

Effect of burn injury on apoptosis and expression of apoptosis-related genes/proteins in skeletal muscles of ratsSemantic proximity Read ↗

Injury-induced suppression of effector T cell immunity requires CD1d-positive APCs and CD1d-restricted NKT cells.Semantic proximity Read ↗

Differential immunological phenotypes are exhibited after scald and flame burns.Semantic proximity Read ↗

Suppressor T-cell levels are unreliable indicators of the impaired immune response following thermal injury.Semantic proximity Read ↗

Nitric oxide contributes to the development of a post-injury Th2 T-cell phenotype and immune dysfunction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.