Article
A genome-wide scan for quantitative trait loci linked to obesity phenotypes among West Africans.
International journal of obesity (2005) - 1 Mar 2005
Chen G, Adeyemo A A, Johnson T, Zhou J, Amoah A, Owusu S, Acheampong J, Agyenim-Boateng K, Eghan B A, Oli J, Okafor G, Abbiyesuku F, Dunston G M, Chen Y, Collins F, Rotimi C
Abstract excerpt
OBJECTIVE: To identify quantitative trait loci (QTL) for three obesity phenotypes: body mass index (BMI), fat mass (FM) and percent body fat (PBF) in West Africans with type 2 diabetes (T2DM). DESIGN: An affected sibling pair (ASP) design, in which both siblings had T2DM. Obesity was analyzed as a quantitative trait using a variance components approach. SUBJECTS: Sib-pairs affected with T2DM from the Africa...
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