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Article

A genome-wide linkage scan for quantitative trait loci underlying obesity related phenotypes in 434 Caucasian families.

Human genetics - 1 Mar 2007

Zhao Lan-Juan, Xiao Peng, Liu Yong-Jun, Xiong Dong-Hai, Shen Hui, Recker Robert R, Deng Hong-Wen

Abstract excerpt

To identify quantitative trait loci (QTLs) that contribute to obesity, we performed a large-scale whole genome linkage scan (WGS) involving 4,102 individuals from 434 Caucasian families. The most pronounced linkage evidence was found at the genomic region 20p11-12 for fat mass (LOD = 3.31) and percentage fat mass (PFM) (LOD = 2.92). We also identified several regions showing suggestive linkage signals (threshold...

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Identifiers

PMID: 17115187
DOI: 10.1007/s00439-006-0286-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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