Article
A genome wide quantitative trait linkage analysis for serum lipids in type 2 diabetes in an African population.
Atherosclerosis - 1 Aug 2005
Adeyemo Adebowale A, Johnson Thomas, Acheampong Joseph, Oli Johnnie, Okafor Godfrey, Amoah Albert, Owusu Samuel, Agyenim-Boateng Kofi, Eghan Benjamin A, Abbiyesuku Fayeofori, Fasanmade Olufemi, Rufus Theresa, Doumatey Ayo, Chen Guanjie, Zhou Jie, Chen Yuanxiu, Furbert-Harris Paulette, Dunston Georgia, Collins Francis, Rotimi Charles
Abstract excerpt
Lipid abnormalities are strongly linked with coronary heart disease and are common in type 2 diabetes. However, little is known about the genetic determinants of serum lipids in African populations. An autosomal genome scan was performed for linkage to five plasma lipid phenotypes (total cholesterol, triglycerides (TG), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C) and VLDL-cholesterol (VLDL-C)) in the...
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