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Article

Anthropometric and cardio-metabolic trait variation and genetic associations in sub-Saharan Africa.

American journal of human genetics - 3 Sept 2026

Hansen Matthew E B, Hazra Ujani, Kim Michelle, Raj Srilakshmi M, Fan Shaohua, Beggs William, Mpoloka Sunungouko Wata, Mokone Gaonyadiwe George, Nyambo Thomas, Meskel Dawit Wolde, Belay Gurja, Hirbo Jibril, Ranciaro Alessia, Lachance Joseph, Tishkoff Sarah A

Abstract excerpt

The genetics of complex traits in Africa has been historically understudied, which can contribute to healthcare inequalities. Here, we present observations of 27 anthropometric, cardiovascular, and blood biomarker measurements across 2,124 individuals from sub-Saharan Africa for whom we also have dense genotype data. First, we identified trait values that differ significantly across populations and subsistence...

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Topics

Female
Humans
Male
Africa South of the Sahara
Anthropometry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Gene Frequency

Genome-Wide Association Study

Genotype

Phenotype

Polymorphism, Single Nucleotide

Sub-Saharan African People

Source

Identifiers

PMID: 42586059
DOI: 10.1016/j.ajhg.2026.07.006

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MAF

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