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Article

dapk1, encoding an activator of a p19ARF-p53-mediated apoptotic checkpoint, is a transcription target of p53.

Oncogene - 17 Feb 2005

Martoriati Alain, Doumont Gilles, Alcalay Myriam, Bellefroid Eric, Pelicci Pier Giuseppe, Marine Jean-Christophe

Abstract excerpt

The p53 tumour suppressor functions as a transcriptional activator, and several p53-inducible genes that play a critical proapoptotic role have been described. Moreover, p53 regulates the expression of various proteins participating in autoregulatory feedback loops, including proteins that negatively control p53 stability (Mdm2 and Pirh2) or modulate stress-induced phosphorylation of p53 on Ser-46 (p53DINP1 or...

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Identifiers

PMID: 15608685
DOI: 10.1038/sj.onc.1208256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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