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Article

Death-associated protein kinase 1 promotes growth of p53-mutant cancers.

The Journal of clinical investigation - 1 Jul 2015

Zhao Jing, Zhao Dekuang, Poage Graham M, Mazumdar Abhijit, Zhang Yun, Hill Jamal L, Hartman Zachary C, Savage Michelle I, Mills Gordon B, Brown Powel H

Abstract excerpt

Estrogen receptor-negative (ER-negative) breast cancers are extremely aggressive and associated with poor prognosis. In particular, effective treatment strategies are limited for patients diagnosed with triple receptor-negative breast cancer (TNBC), which also carries the worst prognosis of all forms of breast cancer; therefore, extensive studies have focused on the identification of molecularly targeted...

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Source

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Identifiers

PMID: 26075823
DOI: 10.1172/JCI70805
PMCID: PMC4563671

Genes

DAPK1
TSC1
TSC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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