Article
A chromatin remodelling complex involved in transcription and DNA processing.
Nature - 3 Aug 2000
Shen X, Mizuguchi G, Hamiche A, Wu C
Abstract excerpt
The packaging of the eukaryotic genome in chromatin presents barriers that restrict the access of enzymes that process DNA. To overcome these barriers, cells possess a number of multi-protein, ATP-dependent chromatin remodelling complexes, each containing an ATPase subunit from the SNF2/SWI2 superfamily. Chromatin remodelling complexes function by increasing nucleosome mobility and are clearly implicated in...
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