Article
A 15 base-pair AT-rich variable number tandem repeat in the type III procollagen gene (COL3A1) as an informative marker for 2q31-2q32.3.
Matrix (Stuttgart, Germany) - 1 Feb 1992
Mays P K, Tromp G, Kuivaniemi H, Ryynänen M, Prockop D J
Abstract excerpt
Segments of repeating DNA, termed variable number tandem repeats, within the genome are often used as polymorphic markers. Here we report such a repeat in the intervening sequence 25 of the type III procollagen gene (COL3A1) located at 2q31-q32.3. The region containing intervening sequence 25 of the COL3A1 gene was amplified using the polymerase chain reaction and the products were analyzed by agarose gel...
Topics
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 2
- Gene Frequency
- Genes
- Genetic Markers
- Humans
- Molecular Sequence Data
- Pedigree
- Polymerase Chain Reaction
- Procollagen
