Article
Immunogenetics of killer cell immunoglobulin-like receptors.
Molecular immunology - 1 Feb 2005
Parham Peter
Abstract excerpt
The killer cell immunoglobulin receptor locus (KIR) on human chromosome 19 encodes activating and inhibitory receptors that are expressed principally by NK cells but also by subpopulations of T cells. For some of the KIR the ligands are known to be MHC class I molecules, for others ligands are elusive. In humans the KIR locus is highly diverse. KIR haplotypes differ in gene content and the individual genes...
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