Article
Expression of a yeast acetyl CoA hydrolase in the mitochondrion of tobacco plants inhibits growth and restricts photosynthesis.
Plant molecular biology - 1 Jul 2004
Bender-Machado Lilia, Bäuerlein Michael, Carrari Fernando, Schauer Nicolas, Lytovchenko Anna, Gibon Yves, Kelly Amelie A, Loureiro Marcello, Müller-Röber Bernd, Willmitzer Lothar, Fernie Alisdair R
Abstract excerpt
Acetyl Coenzyme A (acetyl CoA) is required in the mitochondria to fuel the operation of the Krebs cycle and within the cytosolic, peroxisomal and plastidial compartments wherein it acts as the immediate precursor for a wide range of anabolic functions. Since this metabolite is impermeable to membranes it follows that discrete pathways both for its synthesis and for its utilization must be present in each of these...
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