Reverse genetic characterization of cytosolic acetyl-CoA generation by ATP-citrate lyase in Arabidopsis.

doi:10.1105/tpc.104.026211

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Article

Reverse genetic characterization of cytosolic acetyl-CoA generation by ATP-citrate lyase in Arabidopsis.

The Plant cell - 1 Jan 2005

Fatland Beth L, Nikolau Basil J, Wurtele Eve Syrkin

Abstract excerpt

Acetyl-CoA provides organisms with the chemical flexibility to biosynthesize a plethora of natural products that constitute much of the structural and functional diversity in nature. Recent studies have characterized a novel ATP-citrate lyase (ACL) in the cytosol of Arabidopsis thaliana. In this study, we report the use of antisense RNA technology to generate a series of Arabidopsis lines with a range of ACL...

Topics

ATP Citrate (pro-S)-Lyase
Acetyl Coenzyme A
Arabidopsis
Arabidopsis Proteins
Cell Compartmentation
Cytosol
Down-Regulation
Energy Metabolism
Gene Expression Regulation, Plant
Malonates
Molecular Sequence Data
Phenotype
Plastids
RNA, Antisense
RNA, Messenger
Seeds
Starch
Transgenes

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Identifiers

PMID: 15608338
DOI: 10.1105/tpc.104.026211
PMCID: PMC544498

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