Article
The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD(H) and acetyl-CoA under in vivo conditions.
The EMBO journal - 17 Jul 1995
van Roermund C W, Elgersma Y, Singh N, Wanders R J, Tabak H F
Abstract excerpt
We investigated how NADH generated during peroxisomal beta-oxidation is reoxidized to NAD+ and how the end product of beta-oxidation, acetyl-CoA, is transported from peroxisomes to mitochondria in Saccharomyces cerevisiae. Disruption of the peroxisomal malate dehydrogenase 3 gene (MDH3) resulted...
Topics
- Acetyl Coenzyme A
- Base Sequence
- Biological Transport
- DNA
- Intracellular Membranes
- Malate Dehydrogenase
- Microbodies
- Mitochondria
- Molecular Sequence Data
- Mutation
- NAD
- Oleic Acid
- Oleic Acids
- Permeability
- Saccharomyces cerevisiae