Article
A haplotype-based test of association using data from cohort and nested case-control epidemiologic studies.
Human heredity - 1 Jan 2004
Chen Jinbo, Peters Ulrike, Foster Charles, Chatterjee Nilanjan
Abstract excerpt
Haplotype-based risk models can lead to powerful methods for detecting the association of a disease with a genomic region of interest. In population-based studies of unrelated individuals, however, the haplotype status of some subjects may not be discernible without ambiguity from available locus-specific genotype data. A score test for detecting haplotype-based association using genotype data has been developed...
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