Article
T-cell receptor variable (V) gene usage by lymphoid populations in T-cell lymphoma.
The Journal of pathology - 1 Feb 1992
Smith J L, Lane A C, Hodges E, Reynolds W M, Howell W M, Jones D B, Janson C H
Abstract excerpt
A panel of monoclonal antibodies specific for TcR V gene families was used to study TcR V region expression in 28 cases of malignant and reactive T-cell expansions including four cases of mixed cellularity Hodgkin's disease (HD) and five reactive cases. TcR V beta 5 gene products were represented in three cases of lymphoblastic malignancy (V beta 5.1, V beta 5.2) and two cases of peripheral T-cell lymphoma (PTCL)...
Topics
- Antibodies, Monoclonal
- Gene Expression
- Gene Rearrangement, T-Lymphocyte
- Genotype
- Humans
- Immunohistochemistry
- Lymphoma, T-Cell, Cutaneous
- Phenotype
- Receptors, Antigen, T-Cell
- T-Lymphocytes