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Article

Glucose inhibits meiotic DNA replication through SCFGrr1p-dependent destruction of Ime2p kinase.

Molecular and cellular biology - 1 Jan 2005

Purnapatre Kedar, Gray Misa, Piccirillo Sarah, Honigberg Saul M

Abstract excerpt

In the budding yeast Saccharomyces cerevisiae, the cell division cycle and sporulation are mutually exclusive cell fates; glucose, which stimulates the cell division cycle, is a potent inhibitor of sporulation. Addition of moderate concentrations of glucose (0.5%) to sporulation medium did not inhibit transcription of two key activators of sporulation, IME1 and IME2, but did increase levels of Sic1p, a...

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Identifiers

PMID: 15601864
DOI: 10.1128/MCB.25.1.440-450.2005
PMCID: PMC538797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Glucose inhibits meiotic DNA replication through SCFGrr1p-dependent destruction of Ime2p kinase.PMID 15601864Read ↗

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