Article
Three subunits of the RNA polymerase II mediator complex are involved in glucose repression.
Nucleic acids research - 11 Nov 1995
Balciunas D, Ronne H
Abstract excerpt
Glucose triggers a complex response in yeast which includes induction and repression of a large number of genes. Glucose repression is in part mediated by the Mig1 repressor, a zinc finger protein that binds to the promoters of many glucose repressed genes. However, some genes that are required for gluconeogenic growth are also repressed by a Mig1-independent mechanism. We have isolated mutations in three genes...
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