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Article

Molecular and cellular dissection of mating-type switching steps in Schizosaccharomyces pombe.

Molecular and cellular biology - 1 Jan 2005

Holmes Allyson M, Kaykov Atanas, Arcangioli Benoit

Abstract excerpt

A strand-specific imprint (break) controls mating-type switching in fission yeast. By introducing a thiamine repressible promoter upstream of the mat1 locus, we can force transcription through the imprinted region, erasing the imprint and inhibiting further mating-type switching, in a reversible manner. Starting from a synchronized, virgin M-cell population, we show that the site- and strand-specific break is...

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Identifiers

PMID: 15601851
DOI: 10.1128/MCB.25.1.303-311.2005
PMCID: PMC538788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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