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Article

RNase-sensitive DNA modification(s) initiates S. pombe mating-type switching.

Genes & development - 1 Apr 2004

Vengrova Sonya, Dalgaard Jacob Z

Abstract excerpt

Mating-type switching in fission yeast depends on an imprint at the mat1 locus. Previous data showed that the imprint is made in the DNA strand replicated as lagging. We now identify this imprint as an RNase-sensitive modification and suggest that it consists of one or two RNA residues incorporated into the mat1 DNA. Formation of the imprint requires swi1- and swi3-dependent pausing of the replication fork....

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Share to Chromosomal Proteins, Non-Histone
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Share to Genes, Mating Type, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15059961
DOI: 10.1101/gad.289404
PMCID: PMC387419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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